Fabrication, characterization, and evaluation of microsponge delivery system for facilitated fungal therapy
نویسندگان
چکیده
منابع مشابه
Fabrication, characterization, and evaluation of microsponge delivery system for facilitated fungal therapy
OBJECTIVE The rationale behind present research vocation was to develop and investigate a novel microsponge based gel as a topical carrier for the prolonged release and cutaneous drug deposition of fluconazole (FLZ); destined for facilitated fungal therapy. MATERIALS AND METHODS Microsponges were prepared using quasi-emulsion solvent diffusion method using Eudragit S-100. In the direction of ...
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The aim of the present study was to develop and evaluate microsponge based topical delivery system of acyclovir for sustained and enhanced drug deposition in the skin. Microsponges containing acyclovir were prepared by an emulsion solvent diffusion method. The effect of formulation variable such as drug: polymer ratio, stirring speed, internal phase on the physical characteristics of microspong...
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In the present study controlled release formulation of Indomethacin microsponges were prepared by using Eudragit RS 100, pH independent release retardant polymer and PVA, stabilizer or emulsifier. Microsponges were prepared by Quasi emulsion solvent diffusion method by changing drug polymer ratio (3:1, 4:1, 5:1) and process was optimized. Microsponges were evaluated by micromeritic properties, ...
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Microsponge were prepared by liquid-liquid suspension polymerization of styrene and methyl methacrylate. Microsponges were dispersed in gel prepared by using carbopol 940 and evaluated for drug release using Franz diffusion cell. Free flowing powder with size distribution 30 to 107 μm was obtained. The average drug release from the gels containing microspongic fluconazole was 67.81% in 12 h. dr...
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ژورنال
عنوان ژورنال: Journal of Basic and Clinical Pharmacy
سال: 2016
ISSN: 0976-0105
DOI: 10.4103/0976-0105.177705